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Anne Nilsson

Food based prevention of cardiometabolic diseases and a related cognitive decline

Anne Nilsson studies the effects of potentially “anti-diabetic” dietary substrates on cardiometabolic risk markers and cognitive functions.

A specific focus is to investigate the metabolic “cross-talk” between the gut and the peripheral and central tissues, i.e. the link between colonic metabolism of indigestible carbohydrates (i.e. dietary fibre) and risk markers related to cardiometabolic disorders. It is known that cardiometabolic disorders, such as e.g. diabetes type-2, increase the risk of cognitive decline and development of dementia, including Alzheimer’s disease. Investigations of links between cardiometabolic risk markers and cognitive performance is therefore an important additional research topic. For these purposes, selected foods, food constituents and food concepts are evaluated in human intervention studies.

Research projects

  • Prebiotic Concepts to Regulate Cardiometabolic Rist Factors and Appetite; Colonic fermentation aspects.
  • Barley Prebiotics.
  • On the impact of sweetening agents on glucose regulation, cognitive functioning and gut microbiota; comparing sucrose, steviol glycosides and saccharine.
  • The Gut Brain Axis.

Selected original papers

A Nilsson, E Johansson-Boll, I Björck. (2015). Increased gut hormones and insulin sensitivity index following a 3-d intervention with a barley kernel-based product: a randomised cross-over study in healthy middle-aged subjects. Br J Nut; Aug 11:p. 1-9.

Tovar J, Nilsson A, Johansson M, Björck I.  (2014). Combining functional features of whole-grain barley and legumes for dietary reduction of cardiometabolic risk: a randomised cross-over intervention in mature women.  Br J Nut; 111;(4): p. 706-14.

Nilsson A, Tovar J, Johansson M, Björck I. (2013). A diet based on multiple functional concepts improves cognitive performance in healthy subjects. Nutr Metab; 10(1): p. 49.

Johansson E, Nilsson A, Östman E, Björck I. (2013). Effect of indigestible carbohydrates in barley on glucose metabolism, appetite and voluntary food intake over 16 h in healthy adults, Nutrition J; 12: p. 46.

Nilsson A, Johansson E, Ekström L and Björck I (2013). Effects of a brown bean evening meal on metabolic risk markers, incretins and appetite regulating hormones at a subsequent standardized breakfast. Plos One; 8(4): p. e59985.

Nilsson A, Radeborg K, Salo I and Björck I. (2012). Effects of supplementation with n-3 polyunsaturated fatty acids on cognitive performance and cardiometabolic risk markers in
healthy 51 to 72 years old subjects: a randomized controlled cross-over study
. Nutrition Journal; 11(1): p. 99.

Nilsson A, Radeborg, K., Bjorck, I (2012). Effects on cognitive performance of modulating the postprandial blood glucose profile at breakfast. Eur J Clin Nutr. 66(9): p. 1039-43.

Tovar J, Nilsson A, Johansson M, Eesbo R, Åberg A. M, Johansson U, Bjorck I.  (2012). A diet based on multiple functional concepts improves cardiometabolic risk parameters in healthy subjects.  Nutrition and Metabolism; 9; p. 29.

Nilsson A, Östman E, Bach Knudsen K. E, Holst J.J. and Björck I (2010). A cereal-based evening meal rich in indigestible carbohydrates increases plasma butyrate the next morning.
J Nutr Nov; 140(11): p. 1932-1936.

Nilsson A, Östman E, Holst J.J and Björck I (2008). Including indigestible carbohydrates in the evening meal of healthy subjects improves glucose tolerance, lowers inflammatory markers, and increases satiety after a subsequent standardized breakfast.
The Journal of Nutrition 138(4):p. 732-9.



Anne Nilsson

Food for Health Science Centre
Lund University
Medicon Village
SE-223 81  Lund, Sweden

Tel +46(46)222 000 (switchboard)

VAT number: SE202100321101