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Frida Fåk

Modulation of the gut microbiota using tailored food concepts

Frida Fåk’s research focuses on modulation of the gut microbiota using tailored food concepts to prevent metabolic and inflammatory conditions.
She is Coordinator of the Gut Microbiome Laboratory at Food for Health Science Centre, where the gut microbiota composition and functionality is analysed using next-generation sequencing. Current main research projects include:

  • How do different food components alter the gut microbiota and can microbiome changes be linked to health benefits of foods? – PhD student Nittaya Marungruang
  • The gut microbiome and neuroinflammatory processes – PhD student Nittaya Marungruang
  • Dietary fibre, gut metabolites (short-chain fatty acids, bile acids and LPS) and microbiota composition - PhD-student Tannaz Ghaffarzadegan
  • Nutritional effects of glycerolesters – PhD-student Thao Nguyen
  • Atherosclerosis and the gut and oral microbiota – Collaboration with University of Gothenburg and Faculty of Odontology, Malmö
  • The gut and oral microbiota of participants in the Malmö Offspring Study and Malmö Offspring Dental StudyPhD Olena Prykhodko

 

Peer-reviewed original articles

  1. Modulation of gut microbiota in rats fed high-fat diets by processing whole-grain barley to barley malt. Zhong Y, Nyman M, Fåk F. Mol Nutr Food Res; Epub ahead of print, 2015
  2. Contribution of diet to the composition of the human gut microbiota. Graf D, Di Cagno R, Fåk F, Flint HJ, Nyman M, Saarela M, Watzl B. Review. Microbial Ecology in Health and Disease; 26, 26164. 2015.
  3. Tarmens mikrobiota inverkar på hälsa och sjukdom - Kostintag och genetiska faktorer styr bakterieflorans sammansättning. Nilsson P, Fåk F. Läkartidningen;112. pii: DFH6, 2015
  4. The physico-chemical properties of dietary fibre determine metabolic responses, short-chain fatty acid profiles and gut microbiota composition in rats fed low- and high-fat diets. Fåk F, Jakobsdottir G, Kulcinskaja E, Marungruang N, Matziouridou C, Nilsson U, Stålbrand H, Nyman M. PLoS One; 10, e0127252, 2015
  5. Symptomatic atherosclerosis is associated with an altered gut metagenome. Karlsson FH, Fåk F, Nookaew I, Tremaroli V, Fagerberg B, Petranovic D, Bäckhed F and Nielsen J. Nat Commun; 3:1245, 2012 *
  6. Lactobacillus reuteri prevents diet-induced obesity, but not atherosclerosis, in a strain-dependent fashio in Apoe-/- mice. Fåk F and Bäckhed F. PloS One; 7, e46837, 2012 *
  7. Human oral, gut, and plaque microbiota in patients with atherosclerosis. Koren O*, Spor A*, Felin J*, Fåk F, Stombaugh J, Tremaroli V, Behre CJ, Knight R, Fagerberg B, Ley RE, Bäckhed F. PNAS 108: Suppl 1: 4592-8, 2011. *These authors contributed equally. *
  8. Effects of gut microbiota on obesity and atherosclerosis via modulation of inflammation and lipid metabolism. Caesar R*, Fåk F*, Bäckhed F. J Intern Med 268: 320-328, 2010. Review. *These authors contributed equally.
  9. A novel probiotic mixture exerts a therapeutic effect on experimental autoimmune encephalomyelitis mediated by IL-10 producing regulatory T cells. Lavasani S, Dzhambazov B, Nouri M, Fåk F, Buske S, Molin G, Thorlacius H, Alenfall J, Jeppsson B, Weström B. PLoS One; 5: e9009, 2010
  10. Microbial manipulation of the rat dam changes bacterial colonization and alters properties of the gut in her offspring. Fåk F, Ahrné S, Molin G, Jeppsson B and Weström BR. Am J Physiol: Gastrointest Liver Physiol; 294:G148-54, 2008


 

Frida Fåk

Frida Fåk

Associate Professor

+46 46 222 8389
frida [dot] fak [at] food-health-science [dot] lu [dot] se

Food for Health Science Centre
Lund University
Medicon Village
SE-223 81  Lund, Sweden

Tel +46(46)222 000 (switchboard)

VAT number: SE202100321101